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The concentration of leukotriene D(4) (LTD(4)), which is usually not detectable, was highly increased, whereas LTE(4), the major urinary metabolite in humans, was completely absent

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Kerley C.P., Elnazir B., Faul J., Cormican L

Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology

Its simplicity has made it widely applicable in both emergency and general ward settings

Complete microglial depletion or prolonged broad inhibition may be too severe, especially considering that microglial homeostatic functions are necessary for synaptic maintenance and immune surveillance